Use of measurements from thoracic radiographs to identify high mean left atrium pressure in dogs with myxomatous mitral valve disease
DOI:
https://doi.org/10.5433/1679-0359.2019v40n1p191Keywords:
LA, Ao, left atrium enlargement, pulmonary venous enlargement, thoracic radiography, VHS.Abstract
The aim of this study was to estimate echocardiographic elevated mean left atrium pressure (MLAP) based on measurements from thoracic radiographs and to determine a cut-off value for each radiographic measurement that suggests a high MLAP. A retrospective cross-sectional study was performed to include cases admitted from January 2015 to December 2016. Thoracic radiographic examinations from 93 dogs with and without a high MLAP were included. Specific measurements were made from thoracic radiographs and compared with echocardiographic variables known to indicate high MLAP. This comparison was used to generate equations that allowed the estimation of echocardiographic surrogates from the radiographic measurements. The values indicative of high MLAP were obtained using a regression curve. Formulas that indicated high MLAP were generated using a number of radiographic measurements. Positive echocardiographic findings of high MLAP were used as the gold standard. These formulas helped to predict high MLAP in myxomatous mitral valve disease (MMVD) without the need for echocardiographic examination. The best formula was left atrium (LA):aorta (Ao)echo = 0.03×(vertebral heart score,VHS) + 0.14×(LA) + 0.27×(LA:caudal vena cava (CVC)rad). Values ? 12.2v for VHS, ? 4.5cm for LA, ? 3.3 for LA:Aorad and ? 3.2 for LA:CVCrad suggested high MLAP. Thus, we propose equations, based on measurements from thoracic radiographs, to identify high MLAP. Simple radiographic thoracic measurements, such as LA:CVCrad, can be used to define overload and a high MLAP in dogs with MMVD.Downloads
References
ABBOTT, J. A. Acquired Valvular Disease. In: TILLEY, L. P.; SMITH, F. W. K.; OYAMA, M. A.; SLEEPER, M. M. (Ed.). Manual of canine and feline cardiology. St. Louis: Elsevier Inc., 2008. p. 110-138.
BAVEGEMS, V.; VAN CAELENBERG, A.; DUCHATEAU, L.; SYS, S. U.; VAN BREE, H.; DE RICK, A. Vertebral heart size ranges specific for whippets. Veterinary Radiology and Ultrasound, Harrisburg, v. 46, n. 5, p. 400-403, 2005.
GRECO, A.; MEOMARTINO, L.; RAIANO, V.; FATONE, G.; BRUNETTI, A. Effect of left vs. right recumbency on the vertebral heart score in normal dogs. Veterinary Radiology & Ultrasound, Harrisburg, v. 49, n. 5, p. 454-455, 2008.
HANSSON, K.; HÄGGSTRÖM, J.; KVART, C.; LORD, P. Interobserver variability of vertebral heart size measurements in dogs with normal and enlarged hearts. Veterinary Radiology and Ultrasound, Harrisburg, v. 46, n. 2, p. 122-130, 2005.
HEIDELBERGER, P.; WELCH, P. D. Simulation run length control in the presence of an initial transient. Operations Research, Catonsville, v. 31, n. 6, p. 1109-1144, 1983.
HERNANDEZ-LOPEZ, J.; MACHEN, M. C.; OYAMA, M. A. Radiographic vertebral heart size and left atrial bisecting line: interobserver variability and comparison to echocardiographic left atrial size in dogs with degenerative mitral valve disease. Journal of Veterinary Internal Medicine, Greenwood Village, v. 26, p. 690-822, 2012.
JEPSEN-GRANT, K.; POLLARD, R. E. E.; JOHNSON, L. R. R. Vertebral heart scores in eight dog breeds. Veterinary Radiology and Ultrasound, Harrisburg, v. 54, n. 1, p. 3-8, 2013.
MARIN, L. M.; BROWN, J.; MCBRIEN, C.; BAUMWART, R.; SAMII, V. F.; COUTO, C. G. Vertebral heart size in retired racing greyhounds. Veterinary Radiology & Ultrasound, Harrisburg, v. 48, n. 4, p. 332-334, 2007.
MATTIN, M. J.; BOSWOOD, A.; CHURCH, D. B.; LÓPEZ-ALVAREZ, J.; MCGREEVY, P. D.; O'NEILL, D. G.; THOMSON, P. C.; BRODBELT, D. C. Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary-care veterinary practices in england. Journal of Veterinary Internal Medicine, Greenwood Village, v. 29, n. 3, p. 847-854, 2015.
OYAMA, M. A.; SISSON, D. D.; BULMER, B. J.; CONSTABLE, P. D. Echocardiographic estimation of mean left atrial pressure in a canine model of acute mitral valve insufficiency. Journal of Veterinary Internal Medicine, Greenwood Village, v. 18, n. 5, p. 667-672, 2004.
R DEVELOPMENT CORE TEAM, R: a language and environment for statistical computing. Vienna, Austria : the R Foundation for Statistical Computing, 2011.
SANCHEZ, X.; PRANDI, D.; GARCIA-GUASCH, L.; BADIELLA, L. L.; HERNANDEZ-LOPEZ, J.; MANUBENS, J.; DOMENECH, O.; OYAMA, M. A. New radiographic measurements of left atrial size in dogs with degenerative mitral valve disease: preliminary study. Journal of Veterinary Internal Medicine, Greenwood Village, v. 27, n. 3, p. 604-756, 2013.
THRALL, D. E.; LOSONSKY, J. M. A method for evaluating canine pulmonary circulation dynamics from survey radiographs. Journal of the American Animal Hospital Association, Lakewood, v. 12, p. 457-462, 1976.
WARE, W. A. Aquired valvular and endocardial disease. In: NELSON, R.; COUTO, G. C. (Ed.). Small animal internal medicine. 4th ed. St. Louis: Elsevier Mosby, 2014. p. 115-129.
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