Use of alternative additives for broiler chickens challenged with Eimeria vaccine and Clostridium perfringens
DOI:
https://doi.org/10.5433/1679-0359.2024v45n4p1251Keywords:
Necrotic enteritis, Yeasts, Intestinal permeability.Abstract
The objective of this study was to evaluate the use of alternative additives in diets for broiler chickens challenged with Eimeria vaccine and Clostridium perfringens. A total of 600 broiler chicks were allocated to five treatments in a completely randomized design with six replicates and 20 birds per experimental unit. The treatments were as follows: negative control - basal diet without a growth promoter; positive control - basal diet with the inclusion of 50 g t-1 of 20% avilamycin; diet A - basal diet plus the inclusion of 100 g t-1 of a product based on Macleaya cordata extract; diet B - basal diet plus the inclusion of 1000 g t-1 of a product based on sweet chestnut (Castanea sativa) and red quebracho (Schinopsis lorentzii); and diet C - basal diet plus the inclusion of 100 g t-1 of a product based on prebiotics from Pichia yeast, glutamine, and aluminosilicate. All birds were individually challenged at four days of age with 0.6 mL of the vaccine for Eimeria spp., and at seven and ten days of age with 0.5 mL of Clostridium perfringens. The evaluated parameters included performance, intestinal health, blood parameters, litter quality, and carcass and cut yields. The use of prebiotics (product C) improved weight gain (P<0.05) in the periods from one to 21 days and one to 42 days of age. There was a statistical difference (P<0.05) in the intestinal health index, with the use of product C leading to a lower total lesion score compared to other treatments at 28 days of age. The negative control treatment demonstrated lower intestinal permeability compared to the other treatments (P<0.05). Regarding serum parameters at 14 days of age, uric acid concentrations were higher (P<0.05) in the birds in the negative control group compared to those in the positive control group. The concentration of lactate dehydrogenase was higher (P<0.05) in birds fed products B and C compared to those fed the positive and negative control treatments. Moreover, the concentration of total proteins was higher (P<0.05) in the blood of birds fed product C compared to product A. Cholesterol concentrations at 42 days were lowest (P<0.05) in the treatment with product B. Uric acid concentrations were highest (P>0.05) in the birds receiving additive B and lowest in the group of birds fed product A. Products B and C may serve as substitutes for antibiotics in birds challenged with Eimeria vaccine and Clostridium perfringens.
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