Phytochemical Analysis and Antioxidant Activity Assessment of Croton linearifolius Stem Extracts
DOI:
https://doi.org/10.5433/1679-0375.2025.v46.50875Keywords:
Croton linearifolius, antioxidant activity, phenolic compounds, flavonoidsAbstract
Croton linearifolius is a species with promising medicinal potential. This study investigated the antioxidant activity, total phenolic and flavonoid contents, and conducted chemical prospecting of its ethanolic stem extract and fractions. The extract was obtained by exhaustive percolation with 70% hydroethanolic solution, followed by liquid-liquid partitioning using hexane, dichloromethane, and ethyl acetate. In vitro tests were used for chemical analysis, and antioxidant activity was evaluated by DPPH and FRAP methods. The ethyl acetate fraction showed the highest antioxidant activity (80.62% in DPPH), with elevated phenolic and flavonoid levels, indicating potential for herbal medicine development.
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Copyright (c) 2025 Cleia Teixeira Santos de Franca, Marcel Mark da Silva Passos, Matheus Andrade Rocha Costa, Esaul Lucas Oliveira, Simone Andrade Gualberto
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