Finding the best biological pairwise alignment through genetic algorithm

Finding the best biological pairwise alignment through genetic algorithm

Authors

  • Paulo Mologni Universidade Estadual de Londrina
  • Ailton Akira Shinoda Universidade Estadual de Londrina
  • Carlos Dias Maciel Universidade Estadual de Londrina

DOI:

https://doi.org/10.5433/1679-0375.2004v25n2p129

Keywords:

Biological alignment, Dynamic programming, Genetic algorithm

Abstract

This article describes an alternative method based on Genetic Algorithm (GA) to find the optimal pairwise alignment. It describes the alignment sequence taking into account the chromosome. Each chromosome is associated with a fitness function based on BLOSUM50 substitution matrix.

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Author Biographies

Paulo Mologni, Universidade Estadual de Londrina

M.Sc. Student at the Department of Electrical Engineering, Londrina State University.

Ailton Akira Shinoda, Universidade Estadual de Londrina

Adjunct Professor with the Department of Electrical Engineering, Londrina State University.

Carlos Dias Maciel, Universidade Estadual de Londrina

Adjunct Professor with the Department of Electrical Engineering, Londrina State University.

Published

2004-12-15

How to Cite

Mologni, P., Shinoda, A. A., & Maciel, C. D. (2004). Finding the best biological pairwise alignment through genetic algorithm. Semina: Ciências Exatas E Tecnológicas, 25(2), 129–134. https://doi.org/10.5433/1679-0375.2004v25n2p129

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Section

Original Article

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