Efficiency of the anti-GnRH vaccine for castration of lambs intended for finishing in pastures
DOI:
https://doi.org/10.5433/1679-0359.2021v42n5p2839Keywords:
Andrological evaluation, Seminal characteristics, Immunocastration, sheep.Abstract
It was aimed to evaluate anti-GnRH vaccine efficiency on productive characteristics, seminal performance, size, and histology of testicles of lambs submitted to immunocastration. Twenty contemporary Texel lambs were evaluated, being 10 animals received two doses of 1 mL of anti-GnRH vaccine and 10 received two doses of 1 mL of saline, with an interval of 30 days. Seminal characteristics, weight and histological cut for the testicles, productive performance, and blood parameters were analyzed. Andrological monitoring was carried out every 30 days. All animals were kept on pasture of Urochloa spp. receiving daily supplementation protein-energetic by 90 days. There was effect of immunocastration on slaughter weight (44.3 vs. 48.3 kg), total gain (9.9 vs. 10.3 kg), daily gain (104.5 vs. 108.9 g/day), and feed conversion (5.83 vs. 5.97) respectively to immunocastrated and intact lambs. There was immunocastration effect on testicle weight (0.09 vs. 0.35 g), motility (4.5 vs. 61.0%), vigor (0.40 vs. 3.00), volume (0.09 vs. 0.74 mL) and swirling (0.20 vs. 2.70) in the third semen collection. Immunocastration through two doses of 1 mL of anti-GnRH vaccine with a 30-day interval between doses, causes infertility in sheep and can be adopted for lambs.Metrics
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References
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Machado, D. S., Joner, G., Pereira, L. B., Pötter, L., Brondani, I. L., & Alves, D. C., Fº. (2018). Meta-analysis of the immunocastration technique (anti-GnRH) for male bovines in the finishing phase. Pesquisa Agropecuária Brasileira, 53(8), 961-969. doi: 10.1590/S0100-204X2018000800011
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Price, E. O., Adams, T. E., Huxsoll, C. C., & Borgwardt, R. E. (2003). Aggressive behavior is reduced in bulls actively immunized against gonadotropin-releasing hormone. Journal of Animal Science, 81(2), 411-415. doi: 10.2527/2003.812411x
Restle, J., Alves, D. C., Fº., & Neumann, M. (2000). Efficiency in finishing beef cattle. In J. Restle, Efficiency in the production of beef cattle (pp. 277-303). Santa Maria: Federal University of Santa Maria.
Souza, M. I. L., Urt, M., Ítavo, C. C. B. F., Melo, G. K. A., & Silva, P. C. G., 2019. Reproductive management. In C. C. B. F Ítavo, & L. C. V Ítavo (Eds.), Viva ovinocultura (pp. 239-299). Campo Grande: Editora UFMS.
Zanella, R., Zanella, E. L., Reeves, J. J., Hernandez, J., Motta, A. C. D., & Avila, D. D. (2009). Testicular characteristics of bulls immunosterilized with anti-luteinizing hormone-releasing hormone vaccine. Pesquisa Agropecuária Brasileira, 44(10), 1359-1363. doi: 10.1590/S0100-204X2009001000021
Andreo, N., Bridi, A. M., Silva, C. A. da, Peres, L. M., Giangareli, B. L., Santos, E. R.,… Ferreira, G. A. (2018). Immunocastration and its effects on carcass and meat traits of male pigs. Semina: Ciências Agrárias, 39(6), 2531-2540. doi: 10.5433/1679-0359.2018v39n6p2531
Andreo, N., Bridi, A. M., Tarsitano, M. A., Peres, L. M., Barbon, A. P. A. C., Andrade, E. L. de, & Prohmann, P. E. F. (2013). Influence of immunocastration (Bopriva®) in weight gain, carcass characteristics and meat quality of Nellore. Semina: Ciências Agrárias, 34(6 Supl. 2), 4121-4132. doi: 10.5433/1679-0359.2013v34n6Supl2p4121
Brazilian College of Animal Reproduction (2013). Manual for andrological examination and evaluation of animal semen (2nd ed.). Belo Horizonte: CBRA.
Cook, R. B., Popp, J. D., Kastelic, J. P., Robbins, S., & Harland, R. (2000). The effects of active immunization against GnRH on testicular development, feedlot performance, and carcass characteristics of beef bulls. Journal of Animal Science, 78(11), 2778-2783. doi: 10.2527/2000.78112778x
Earl, E. R., Waterston, M. M., Aughey, E., Harvey, M. J., Matschke, C., Colston, A., & Ferro, V. A. (2006). Avaliação de duas formulações de vacina à base de GnRH-I na função testicular de cordeiros inteiros de carneiro cruzado Suffolk. Vaccine, 24(16), 3172-3183. doi: 10.1016/j.vaccine.2006.01.041
Franciscato, C., Lopes, S. T. D. A., Veiga, Â. P. M., Martins, D. B., Emanuelli, M. P., & Oliveira, L. S. S. (2006). Atividade sérica das enzimas AST, CK e GGT em cavalos Crioulos. Pesquisa Agropecuária Brasileira, 41(10), 1561-1565. doi: 10.1590/S0100-204X2006001000014
Gogić, M., Radović, Č., Čandek-Potokar, M., Petrović, M., Radojković, D., Parunović, N., & Savić, R. (2019). Effect of immunocastration on sex glands of male Mangulica (Swallow-bellied Mangalitsa) pigs. Revista Brasileira de Zootecnia, 48(e20180286), 1-8. doi: 10.1590/rbz4820180286
Gómez, J. F. M., Saran Netto, A., Antonelo, D. S., Silva, S. L., Sene, G. A., Silva, H. B.,... Silva, L. (2017). Effects of immunocastration on the performance and meat quality traits of feedlot-finished Bos indicus (Nellore) cattle. Animal Production Science, 59(1), 183-190. doi: 10.1071/AN17102
Han, X., Zhou, M., Cao, X., Du, X., Meng, F., Bu, G.,... Zeng, X. (2019). Mechanistic insight into the role of immunocastration on eliminating skatole in boars. Theriogenology, 131(6), 32-40. doi: 10.1016/j. theriogenology.2019.03.017
Janett, F., Gerig, T., Tschuor, A. C., Amatayakul-Chantler, S., Walker, J., Howard, R.,… Thun, R. (2012). Vaccination against gonadotropin-releasing factor (GnRF) with Bopriva significantly decreases testicular development, serum testosterone levels and physical activity in pubertal bulls. Theriogenology, 78(1), 182-188. doi: 1010.1016/j.theriogenology.2012.01.035
Lents, M. P., Barbosa, L. P., Santana, A. L. A., Pinheiro, E. E. G., Mugabe, L. C., Biscarde, C. E. A.,... Souza, R. S. (2018). Immunocastration of goats using anti-gonadotrophin releasing hormone vaccine. Theriogenology, 114(1), 7-13. doi: 10.1016/j.theriogenology.2018.03.013
Lugar, D. W., Rhoads, M. L., Clark-Deener, S. G., Callahan, S. R., Revercomb, A. K., Prusa, K. J., & Estienne, M. J. (2017). Immunological castration temporarily reduces testis size and function without long-term effects on libido and sperm quality in boars. Animal, 11(4), 643-649. doi: 10.1017/S1751731 116002081
Machado, D. S., Joner, G., Pereira, L. B., Pötter, L., Brondani, I. L., & Alves, D. C., Fº. (2018). Meta-analysis of the immunocastration technique (anti-GnRH) for male bovines in the finishing phase. Pesquisa Agropecuária Brasileira, 53(8), 961-969. doi: 10.1590/S0100-204X2018000800011
National Research Council (2007). Nutrient requirements of small ruminants: sheep, goats, cervids, and new world camelids. Washington, DC: The National Academies Press.
Needham, T., Lambrechts, H., & Hoffman, L. C. (2019). Extending the interval between second vaccination and slaughter: II. Changes in the reproductive capacity of immunocastrated ram lambs. Animal, 13(9), 1962-1971. doi: 10.1017/S1751731118003592
Osório, J. C. D. S., Osório, M. T. M., & Sañudo, C. (2009). Características sensoriais da carne ovina. Revista Brasileira de Zootecnia, 38(SPE), 292-300. doi: 10.1590/S1516-35982009001300029
Price, E. O., Adams, T. E., Huxsoll, C. C., & Borgwardt, R. E. (2003). Aggressive behavior is reduced in bulls actively immunized against gonadotropin-releasing hormone. Journal of Animal Science, 81(2), 411-415. doi: 10.2527/2003.812411x
Restle, J., Alves, D. C., Fº., & Neumann, M. (2000). Efficiency in finishing beef cattle. In J. Restle, Efficiency in the production of beef cattle (pp. 277-303). Santa Maria: Federal University of Santa Maria.
Souza, M. I. L., Urt, M., Ítavo, C. C. B. F., Melo, G. K. A., & Silva, P. C. G., 2019. Reproductive management. In C. C. B. F Ítavo, & L. C. V Ítavo (Eds.), Viva ovinocultura (pp. 239-299). Campo Grande: Editora UFMS.
Zanella, R., Zanella, E. L., Reeves, J. J., Hernandez, J., Motta, A. C. D., & Avila, D. D. (2009). Testicular characteristics of bulls immunosterilized with anti-luteinizing hormone-releasing hormone vaccine. Pesquisa Agropecuária Brasileira, 44(10), 1359-1363. doi: 10.1590/S0100-204X2009001000021
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2021-07-02
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Bonin, M. de N., Ítavo, C. C. B. F., Ítavo, L. C. V., Gomes, M. de N. B., Sampaio, B. F. B., Difante, G. dos S., Gurgel, A. L. C., Arco, T. F. F. de S., Ferelli, K. L. S. M., & Surita, L. M. A. (2021). Efficiency of the anti-GnRH vaccine for castration of lambs intended for finishing in pastures. Semina: Ciências Agrárias, 42(5), 2839–2850. https://doi.org/10.5433/1679-0359.2021v42n5p2839
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