Canine transmissible venereal tumor with encephalic metastasis

Authors

  • Ciciane Pereira Marten Fernandes Universidade Federal de Pelotas
  • Luiz Fernando Jantzen Gaspar Universidade Federal de Pelotas
  • Ana Raquel Mano Meinerz Universidade Federal de Pelotas
  • Fabiane Borelli Grecco Universidade Federal de Pelotas
  • Márcia Oliveira Nobre Universidade Federal de Pelotas
  • Marlete Brum Cleff Universidade Federal de Pelotas

DOI:

https://doi.org/10.5433/1679-0359.2013v34n6Supl2p3929

Keywords:

Dog, Transmissible venereal tumor, Metastases, Encephalon, Doxorubicin.

Abstract

 

The first case in Brazil of vaginal TVT with metastasis for the central nervous system is reported, as well as the presence of cutaneous, eye and lung metastases and describes the resistance of the TVT to treatment with vincristine. The TVT is a contagious neoplasm that occurs mainly in places where there is no dog population control, and currently, resistance of these tumor cells to conventional treatment with vincristine has been demonstrated. A mongrel female dog of about five years old, weighing 9.2 kg, with a history of vaginal bleeding for more than six months was attended. After cytological diagnosis, treatment with chemotherapy was recommended. There was resistance to chemotherapy treatment with vincristine sulfate, advocating the use of doxorubicin. It is suspected that tumor development in the central nervous system possibly occurred because the doxorubicin was not capable of crossing the hematoencephalic barrier, along with resistance to vincristine.

 

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Author Biographies

Ciciane Pereira Marten Fernandes, Universidade Federal de Pelotas

Discente de Doutorado em Ciência Animal, Universidade Federal de Pelotas, UFPEL, Pelotas, RS.

Luiz Fernando Jantzen Gaspar, Universidade Federal de Pelotas

Prof. Dr. do Deptº de Clínicas Veterinária, UFPEL, Pelotas, RS.

Ana Raquel Mano Meinerz, Universidade Federal de Pelotas

Profª Drª do Deptº de Clínicas Veterinária, UFPEL, Pelotas, RS.

Fabiane Borelli Grecco, Universidade Federal de Pelotas

Profª Drª do Deptº de Patologia Animal, UFPEL, Pelotas, RS.

Márcia Oliveira Nobre, Universidade Federal de Pelotas

Profª Drª do Deptº de Clínicas Veterinária, UFPEL, Pelotas, RS.

Marlete Brum Cleff, Universidade Federal de Pelotas

Profª Drª do Deptº de Clínicas Veterinária, UFPEL, Pelotas, RS.

Published

2013-12-17

How to Cite

Fernandes, C. P. M., Gaspar, L. F. J., Meinerz, A. R. M., Grecco, F. B., Nobre, M. O., & Cleff, M. B. (2013). Canine transmissible venereal tumor with encephalic metastasis. Semina: Ciências Agrárias, 34(6Supl2), 3929–3934. https://doi.org/10.5433/1679-0359.2013v34n6Supl2p3929

Issue

Section

Case Reports

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