Estudo eletroquímico do processo de eletrooxidação da amitriptilina empregando sensor a base de pasta de carbono contendo DNA imobilizado em matriz inorgânica

João Paulo Marco; Keyller Bastos Borges; César Ricardo Teixeira Tarley; Emerson Schwingel Ribeiro; Arnaldo César Pereira

doi:10.5433/1679-0375.2015v36n2p133

Electrochemical study of oxidation process of amitriptiline using sensor based on carbon paste containing immobilized DNA on inorganic matrix

Authors

João Paulo Marco Universidade Federal de São João del Rei (UFSJ)
Keyller Bastos Borges Universidade Federal de São João del Rei (UFSJ)
César Ricardo Teixeira Tarley Universidade Estadual de Londrina (UEL)
Emerson Schwingel Ribeiro Universidade Federal do Rio de Janeiro (UFRJ)
Arnaldo César Pereira Universidade Federal de São João del Rei (UFSJ)

DOI:

https://doi.org/10.5433/1679-0375.2015v36n2p133

Keywords:

Antidepressant, Electrochemical behavior, Oxidation process

Abstract

In the present work the voltammetric behavior and the electroxidation process of amitriptiline (AMT) in electrochemical sensor based on carbon paste containing DNA immobilized on the inorganic matrix prepared by sol-gel process (SiO₂/Al₂O₃/Nb₂O₅). The method of Laviron verified that the electroxidation process of AMT is irreversible and high speed of electron transfer. The study of the oxidation of AMT and influence of pH showed slope of 0.059 V/pH (similar the nernstian system: 0.0592 V/pH) suggesting that it involves the transfer of one proton and one electron.

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Author Biographies

João Paulo Marco, Universidade Federal de São João del Rei (UFSJ)

Departamento de Ciências Naturais / Analitica: Eletroanalitica

Keyller Bastos Borges, Universidade Federal de São João del Rei (UFSJ)

Departamento de Ciencias Naturais / Analitica

César Ricardo Teixeira Tarley, Universidade Estadual de Londrina (UEL)

Departamento de Química, Centro de Ciências Exatas

Emerson Schwingel Ribeiro, Universidade Federal do Rio de Janeiro (UFRJ)

Departamento de Química Inorgânica, Instituto de Química

Arnaldo César Pereira, Universidade Federal de São João del Rei (UFSJ)

Departamento de Ciências Naturais / Analitica:Eletroanalítica

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Published

2015-10-17

How to Cite

Marco, J. P., Borges, K. B., Tarley, C. R. T., Ribeiro, E. S., & Pereira, A. C. (2015). Electrochemical study of oxidation process of amitriptiline using sensor based on carbon paste containing immobilized DNA on inorganic matrix. Semina: Ciências Exatas E Tecnológicas, 36(2), 133–144. https://doi.org/10.5433/1679-0375.2015v36n2p133

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Issue

Vol. 36 No. 2 (2015)

Section

Original Article

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