Study of the celular growth cinetics in kidney all cultures treated with citrinin

Authors

  • Aline Artioli Machado Yamamura Universidade Estadual de Londrina
  • Maria Helena do Carmo Lagrota Universidade Federal do Rio de Janeiro
  • Luiz Celso Hygino da Cruz Universidade Federal Rural do Rio de Janeiro
  • Marco Antonio da Rocha Universidade Estadual de Londrina

DOI:

https://doi.org/10.5433/1679-0359.1991v12n1p9

Keywords:

Citrinin, Citotoxicity, Cell culture.

Abstract

The cytotoxic effect of citrinin on three renal cells,  LLC-MK2, PK-15 and MDBK, has been studied regarding the fact that the kidney is the target organ affected by citrinin. The citrinin acted intensively on the growth of the cells, inhibiting it mainly in the first hours. There was a decrease of the LLC-MK2, cell cultivation concerning the cultivation treated with micotoxin after 24 hours of incubation. Although less intensively, the same thing happened to the PK-15 and the MDBK cultivations. The statements mentioned above were confirmed by statistic analyses.

 

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Author Biographies

Aline Artioli Machado Yamamura, Universidade Estadual de Londrina

Departamento de Medicina Veterinária Preventiva, Patologia Animal e Zootecnia / CCA – Universidade Estadual de Londrina.

Maria Helena do Carmo Lagrota, Universidade Federal do Rio de Janeiro

Departamento de Virologia do Instituto de Microbiologia da Universidade Federal do Rio de Janeiro.

Luiz Celso Hygino da Cruz, Universidade Federal Rural do Rio de Janeiro

 

Instituto de Biologia da Universidade Federal Rural do Rio de Janeiro

Marco Antonio da Rocha, Universidade Estadual de Londrina

 

Departamento de Medicina Veterinária Preventiva, Patologia Animal e Zootecnia / CCA – Universidade Estadual de Londrina.

Published

1991-03-09

How to Cite

Yamamura, A. A. M., Lagrota, M. H. do C., Cruz, L. C. H. da, & Rocha, M. A. da. (1991). Study of the celular growth cinetics in kidney all cultures treated with citrinin. Semina: Ciências Agrárias, 12(1), 9–14. https://doi.org/10.5433/1679-0359.1991v12n1p9

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