Canine visceral leishmaniasis in riverside communities of the Cuiabá river watershed
DOI:
https://doi.org/10.5433/1679-0359.2019v40n6Supl2p3313Keywords:
Leishmania infantum, Riverside communities, Dog, Cuiaba.Abstract
Visceral Leishmaniasis (VL) is a parasitic zoonosis expanding in Brazil. Several municipalities in the state of Mato Grosso including those on the river Cuiabá have reported the incidence of both human and canine cases and the identification of sandfly vector, Lutzomyia longipalpis and Lu. cruzi. Dogs are considered the main reservoir of Leishmania chagasi in the urban areas, hence, we devised a cross-sectional study aimed at assessing the prevalence of the infection in the dogs of riverside communities on Cuiabá River watershed by parasitological (parasitic isolation in culture), serological, and molecular methods. Of the 248 surveyed dogs, 24 were positive in enzyme linked immunosorbent assay (ELISA) or immunofluorescence antibody test (IFAT), with a prevalence of 9.7%. The riverside communities located in the town of Santo Antonio do Leverger displayed a higher prevalence of the disease than the cities of Cuiabá and Várzea Grande; however, the difference was not statistically significant (p > 0.05). Dogs born in the communities had a 3.24-fold higher risk of acquiring the infection. Promastigote were isolated in the axenic culture from the bone marrow samples and intact skin. Further, DNA of Leishmania sp. was detected in the bone marrow samples, lymph nodes, leukocyte cover, and skin of only one examined dog. These samples were sequenced and they showed 99% homology to L. infantum. To conclude, we observed a higher prevalence of infection in Riverside communities of Santo Antonio do Leverger and the confirmation of autochthony in these areas justifies the surveillance actions to minimise the risk of transmission within the riverine community itself, besides its dissemination to other areas by tourism.Downloads
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References
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MISSAWA, N. A.; BORBA, J. F. Leishmaniose visceral no município de Várzea Grande, estado de Mato Grosso, no período de 1998 a 2007. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 42, n. 5, p. 496-502, 2009. DOI: 10.1590/S0037-86822009000500005.
MISSAWA, N. A.; MICHALSKY, E. M.; FORTES-DIAS, C. L.; DIAS, E. S. Lutzomyia longipalpis naturally infected by Leishmania (L.) chagasi in Várzea Grande, Mato Grosso State, Brazil, an area of intense transmission of visceral leishmaniasis. Caderno de Saúde Pública, Rio de Janeiro, v. 26, n. 12, p. 2414-2419, 2010. DOI: 10.1590/S0102-311X2010001200020.
QUINNELL, R. J.; COURTENAY, O. Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis. Parasitology, London, v. 136, n. 14, p. 1915-1934, 2009. DOI: 10.1017/S0031182009991156.
SMITH, A.; CLARK, P.; AVERIS, S.; LYMBERY, A. J.; WAYNE, A. F.; MORRIS, K. D.; THOMPSON, R. C. Trypanosomes in a declining species of threatened Australian marsupial, the brush-tailed bettong Bettongia penicillata (Marsupialia: Potoroidae). Parasitology, London, v. 135, n. 11, p. 1329-1335, 2008. DOI: 10.1017/S0031182008004824.
ALMEIDA, A. B. P. F.; SOUSA, V. R. F.; CRUZ, F. A. C. S.; DAHROUG, M. A. A.; FIGUEIREDO, F. B.; MADEIRA, M. F. Canine visceral leishmaniasis: seroprevalence and risk factors in Cuiabá, Mato Grosso, Brazil. Revista Brasileira de Parasitologia Veterinária, Jaboticabal, v. 21, n. 4, p. 359-365, 2012. DOI: 10.1590/S1984-29612012005000005.
ALMEIDA, A. B. P. F.; SOUSA, V. R. F.; GASPARETTO, N. D.; SILVA, G. F. R. da; FIGUEIREDO, F. B.; DUTRA, V.; NAKAZATO, L.; MADEIRA, M. F. Canine visceral leishmaniasis: diagnostic approaches based on polymerase chain reaction employing different biological samples. Diagnostic Microbiology and Infectious Disease, Nova Iorque, v. 76, n. 3, p. 321-324, 2013. DOI: 10.1016/j.diagmicrobio.2013.03.017.
BRITO, V. N.; ALMEIDA, A. B. P. F.; NAKAZATO, L.; DUARTE, R.; SOUZA, C. O.; SOUSA, V. R. F. Phlebotomine fauna, natural infection rate and feeding habits of Lutzomyia cruzi in Jaciara, state of Mato Grosso, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 7, p. 899-904, 2014. DOI: 10.1590/0074-027614011.
BRUHN, F. R. P.; MORAIS, M. H. F.; CARDOSO, D. L.; BRUHN, N. C. P.; FERREIRA, F.; ROCHA, C. M. B. M. Spatial and temporal relationships between human and canine visceral leishmaniases in Belo Horizonte, Minas Gerais, 2006-2013. Parasites & Vectors, Londres, v. 11, n. 1, p. 372-382, 2018. DOI: 10.1186/s13071-018-2877-6.
COURA-VITAL, W.; REIS, A. B.; REIS, L. E.; BRAGA, S. L.; ROATT, B. M.; AGUIAR-SOARES, R. D.; MARQUES, M. J.; VELOSO, V. M.; CARNEIRO, M. Canine visceral leishmaniasis: incidence and risk factors for infection in a cohort study in Brazil. Veterinary Parasitology, Amsterdam, v. 197, n. 3- 4, p. 411-417, 2013. DOI: 10.1016/j.vetpar.2013.07.031.
DEGRAVE, W.; FERNANDES, O.; CAMPBELL, D.; BOZZA, M.; LOPES, U. Utilization of molecular probes and PCR for detection and typing of Leishmania - a mini-review. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 89, n. 3, p. 463-469, 1994. DOI: 10.1590/S0074-02761994000300032.
FUJIMORI, M.; ALMEIDA, A. B. P. F.; DIAS, A. F. L. R.; RODRIGUES, J. Y.; NAKAZATO, L.; MADEIRA, M. F.; SOUSA, V. R. F. Prevalence and associated factors of canine visceral leishmaniasis in na endemic area of Mato Grosso, Brazil. Acta Scientiae Veterinariae, Porto Alegre, v. 44, n. 1, p. 1424-1430, 2016. DOI: 0.22456/1679-9216.81301.
GOMES, A. H. S.; FERREIRA, I. M. R.; LIMA, M. L. S. R.; CUNHA, E. A.; GARCIA, A. S.; ARAÚJO, M. F. L.; PEREIRA-CHIOCCOLA, V. L. PCR identification of Leishmania in diagnosis and control of canine leishmaniasis. Veterinary Parasitology, Amsterdam, v. 144, n. 3-4, p. 234-241, 2007. DOI: 10.1016/j.vetpar.2006.10.008.
GUARIM, V. L. M. S. A educação e a sustentabilidade ambiental em comunidades Ribeirinhas de Mato Grosso, Brasil. Boletim do Museu Paraense Emílio Goeldi, sér. Ciências Humanas, Belém, v. 1, n. 1, p. 7-44, 2005.
HUEB, M.; ASSIS, S. B.; GUIMARAES, E. E. D.; ROSA, D. L.; FONTES, C. J. F. Ocorrência de transmissão autóctone de leishmaniose visceral em Mato Grosso. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 29, n. 3, p. 281-282, 1996. DOI: 10.1590/S0037-86821996000300010.
MELÉNDEZ-LAZO, A.; ORDEIX, L.; PLANELLAS, M.; PASTOR, J.; SOLANO-GALLEGO, L. Clinicopathological findings in sick dogs naturally infected with Leishmania infantum: comparison of five differents clinical classification systems. Research in Veterinary Science, Londres, v. 117, p. 18-27, 2018. DOI: 10.1016/j.rvsc.2017.10.011.
MISSAWA, N. A.; BORBA, J. F. Leishmaniose visceral no município de Várzea Grande, estado de Mato Grosso, no período de 1998 a 2007. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 42, n. 5, p. 496-502, 2009. DOI: 10.1590/S0037-86822009000500005.
MISSAWA, N. A.; MICHALSKY, E. M.; FORTES-DIAS, C. L.; DIAS, E. S. Lutzomyia longipalpis naturally infected by Leishmania (L.) chagasi in Várzea Grande, Mato Grosso State, Brazil, an area of intense transmission of visceral leishmaniasis. Caderno de Saúde Pública, Rio de Janeiro, v. 26, n. 12, p. 2414-2419, 2010. DOI: 10.1590/S0102-311X2010001200020.
QUINNELL, R. J.; COURTENAY, O. Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis. Parasitology, London, v. 136, n. 14, p. 1915-1934, 2009. DOI: 10.1017/S0031182009991156.
SMITH, A.; CLARK, P.; AVERIS, S.; LYMBERY, A. J.; WAYNE, A. F.; MORRIS, K. D.; THOMPSON, R. C. Trypanosomes in a declining species of threatened Australian marsupial, the brush-tailed bettong Bettongia penicillata (Marsupialia: Potoroidae). Parasitology, London, v. 135, n. 11, p. 1329-1335, 2008. DOI: 10.1017/S0031182008004824.
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Published
2019-09-30
How to Cite
Sousa, V. R. F., Dias, Álvaro F. de L. R., Rodrigues, J. Y., Torres, M. de M., Moreira, J. M. A. R., Nakazato, L., … Almeida, A. do B. P. F. de. (2019). Canine visceral leishmaniasis in riverside communities of the Cuiabá river watershed. Semina: Ciências Agrárias, 40(6Supl2), 3313–3320. https://doi.org/10.5433/1679-0359.2019v40n6Supl2p3313
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