Abstract
The cytotoxic effect of citrinin on three renal cells, LLC-MK2, PK-15 and MDBK, has been studied regarding the fact that the kidney is the target organ affected by citrinin. The citrinin acted intensively on the growth of the cells, inhibiting it mainly in the first hours. There was a decrease of the LLC-MK2, cell cultivation concerning the cultivation treated with micotoxin after 24 hours of incubation. Although less intensively, the same thing happened to the PK-15 and the MDBK cultivations. The statements mentioned above were confirmed by statistic analyses.

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Copyright (c) 1991 Aline Artioli Machado Yamamura, Maria Helena do Carmo Lagrota, Luiz Celso Hygino da Cruz, Marco Antonio da Rocha
