Tecido adiposo como fonte de células tronco mesenquimais no tratamento da tendinite equina

Armando de Mattos Carvalho; Carlos Alberto Hussni; Ana Liz Garcia Alves

doi:10.5433/1679-0359.2016v37n6p4179

Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment

Authors

Armando de Mattos Carvalho Universidade de Cuiabá, Universidade Federal de Minas Gerais
Carlos Alberto Hussni Universidade Estadual Paulista
Ana Liz Garcia Alves Universidade Estadual Paulista

DOI:

https://doi.org/10.5433/1679-0359.2016v37n6p4179

Keywords:

Tendon, Therapy, Stem cells, Regenerative medicine.

Abstract

Tendinitis is an important high-relapse-rate disease, which compromises equine performance and may result in early athletic life end to affected animals. Many therapies have been set to treat equine tendinitis; however, just few result in improved relapse rates, quality of extracellular matrix (ECM) and increased biomechanical resistance of the treated tissue. Due to advances in the regenerative medicine, promising results were initially obtained through the implantation of mesenchymal stem cells (MSC) derived from the bone marrow in the equine tendon injury. Since then, many studies have been using MSCs from different sources for therapeutic means in equine. The adipose tissue has appeared as feasible MSC source. There are promising results involving equine tendinitis therapy using mesenchymal stem cells from adipose tissue (AdMSCs).

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Author Biographies

Armando de Mattos Carvalho, Universidade de Cuiabá, Universidade Federal de Minas Gerais

Prof. Dr., Biociência Animal, Universidade de Cuiabá, UNIC, Cuiabá, MT, Prof. Dr. Adjunto, Departamento de Clínica e Cirurgia Veterinárias, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte, MG, Brasil.

Carlos Alberto Hussni, Universidade Estadual Paulista

Profª Drª Adjunto, Departamento de Cirurgia e Anestesiologia Veterinária, Universidade Estadual Paulista, UNESP, Botucatu, SP, Brasil.

Ana Liz Garcia Alves, Universidade Estadual Paulista

Profª Drª Adjunto, Departamento de Cirurgia e Anestesiologia Veterinária, Universidade Estadual Paulista, UNESP, Botucatu, SP, Brasil.

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Published

2016-12-14

How to Cite

Carvalho, A. de M., Hussni, C. A., & Alves, A. L. G. (2016). Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment. Semina: Ciências Agrárias, 37(6), 4179–4192. https://doi.org/10.5433/1679-0359.2016v37n6p4179

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Issue

Vol. 37 No. 6 (2016)

Section

Review Article

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