Analysis of biomarkers in nursing workers in hospital settings: an integrative review

Authors

DOI:

https://doi.org/10.5433/anh.2025v7.id51112

Keywords:

Biomarkers, Nurses, Nursing Staff, Hospital, Shift Work Schedule

Abstract

Introduction: biomarkers have been widely used to assess and diagnose diseases in workers, including nursing professionals, who work in settings that favor physical and mental illness. Objective: to analyze evidence available in literature on biomarkers in nursing workers in hospital settings. Methods: this was an integrative literature review. The search for primary studies was carried out on the Internet in major databases. Search expressions were used for words and descriptors related to the topic. Results: 852 articles were obtained, which, after initial analysis, resulted in 25 articles that constituted the review. The authors included 197 researchers from various universities and institutions, with publications that occurred between 2006 and 2021. The total number of workers who had their markers investigated was 2,975, of various nationalities. In these studies, several biomarkers were identified, measured in different samples such as blood, saliva, urine and hair. The dosages performed were through samples of cortisol, 8-OHdG, melatonin, trace elements, albumin, number of lymphocytes and their various types, HHV-6, trihalomethane, interleukins, interferon, among others. It was observed that the greatest emphasis of studies was on the dosage of cortisol. Conclusions: the workers investigated presented changes in these biomarkers in all the countries investigated, showing the precariousness of the work they perform, with occupational risks and possible risks of illness.

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Author Biographies

Maria Lucia do Carmo Cruz Robazzi, Federal University of Alfenas

Nurse. Senior Professor at the Ribeirão Preto School of Nursing, University of São Paulo. Visiting Professor at the Federal University of Alfenas, MG.

Aida Maria de Oliveira Cruz Mendes, Nursing School of Coimbra

Retired Coordinating Professor of the Nursing School of Coimbra, Portugal

Andressa Fernanda Silva, University of São Paulo

Nurse. PhD in Science from the University of São Paulo, Ribeirão Preto School of Nursing. Ribeirão Preto - SP, Brazil.

Fábio de Souza Terra, Federal University of Alfenas

Nurse. PhD in Science from the Ribeirão Preto School of Nursing at the University of São Paulo (EERP-USP). Associate Professor at the Federal University of Alfenas.

Luiz Almeida da Silva, Federal University of Catalao

Nurse. Post-Doctorate in Sciences. Federal University of Catalão. Catalão, Goiás, Brazil.

Márcia Teles de Oliveira Gouveia, Federal University of Piauí

Nurse. PhD in Science. Federal University of Piauí, Teresina-Pi. Brazil.

Rita de Cássia Marchi Barcelos Dalri, University of São Paulo

Nurse, postdoctoral degree in Sciences. Associate professor in the Professional Master's Program at the Ribeirão Preto School of Nursing - USP

Sergio Valverde Marques Santos, Federal University of Alfenas

Nurse. PhD in Health Sciences, Universidade Federal de Alfenas, Alfenas, Minas Gerais, Brazil.

Vanessa Augusto Bardaquim, Araraquara Idoso Reference Center

Nurse. PhD in Science. Nurse in Specialized Care - Araraquara Elderly Reference Center - CRIA. Araraquara, São Paulo, Brazil.

Liliana Amorim Alves Scandiuzzi, University of São Paulo

Speech therapist. PhD in Science from the Ribeirão Preto School of Nursing at the University of São Paulo (EERP-USP). Owner and Technical Manager of Auric Hearing Center

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Published

2025-04-16

How to Cite

Robazzi, M. L. do C. C., Mendes, A. M. de O. C., Silva, A. F., Terra, F. de S., da Silva, L. A., Gouveia, M. T. de O., … Scandiuzzi, L. A. A. (2025). Analysis of biomarkers in nursing workers in hospital settings: an integrative review. Advances in Nursing and Health, 7, 1–21. https://doi.org/10.5433/anh.2025v7.id51112

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Section

Artigo de Revisão