Aline Artioli Machado Yamamura – alineartioli@uel.br Departamento de Medicina Veterinária Preventiva, Patologia Animal e Zootecnia - CCA/Universidade Estadual de Londrina.
DOI:
https://doi.org/10.5433/1679-0359.1990v11n1p12Keywords:
Micotoxin, Citrinin and citotoxicity.Abstract
The cytotoxic effect of citrinin on three renal cells, i.e. LLC-MK2, PK-15 and MDBK has been studied regarding the fact that the kidney is the target organ affected by citrinin. After reaching the highest non-toxic concentrations of three cultivations, the morphological alterations of the cells were observed. The culture of MDBK cells has showed distinct morphological alterations. One of them is the chromtolisis of the nuclear material.
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