Children with brain tumors: a study of nutritional status on hospital admission

Renata Candido Tsutsumi; Patrícia da Graça Leite Speridião

doi:10.5433/1679-0367.2021v42n1p51

Authors

Renata Candido Tsutsumi Programa de Pós-Graduação em Alimento, Nutrição e Saúde. Universidade Federal de São Paulo - Campus Baixada Santista. https://orcid.org/0000-0002-5688-6352
Patrícia da Graça Leite Speridião Universidade Federal de São Paulo - Campus Baixada Santista https://orcid.org/0000-0002-5276-9001

DOI:

https://doi.org/10.5433/1679-0367.2021v42n1p51

Keywords:

Brain tumors, Pediatrics, Nutritional status

Abstract

Objective: to assess the nutritional status of children with brain tumors on hospital admission and to verify whether the nutritional status varies according to the type of tumor. Methods: anthropometric data of 30 children between 2 and 10 years old, of both sexes, with brain tumors and admitted to a hospital in the city of São Paulo, Brazil, were evaluated. Secondary data collection allowed to assess and classify the Z-scores of the body mass index, percentage of adequacy of the triceptal skinfold and the arm muscle circumference, carried out between the years 2004 and 2011. Results: The frequencies of brain tumors were: 33.3% astrocytic, 40% embryonal, 10% of the seal region and 16.6% ependimals. The median age and body mass index Z scores were 5.5 years (4.0 and 7.0) and 0.66 SD (- 1.41 and 0.87), respectively. The median percentage of adequacy of arm muscle circumference was 98% (88.9 and 103.2) and the triceptal skinfold was 83.2% (57.0 and 106.6). As for nutritional status, 21 (70%) of the children were eutrophic; 7 (23.3%) overweight and 2 (6.7%) with malnutrition/wasting showing no significant difference between groups of brain tumors (p = 0.721). The percentages of adequacy of the triceptal skinfold and of the arm muscle circumference also showed no significant difference between the different types of brain tumors (p = 0.865 and p = 0.860, respectively). Conclusion: at the time of hospital admission, the children were in good nutritional status, regardless of the type of brain tumor.

Downloads

Download data is not yet available.

Author Biographies

Renata Candido Tsutsumi, Programa de Pós-Graduação em Alimento, Nutrição e Saúde. Universidade Federal de São Paulo - Campus Baixada Santista.

M.Sc. in Food, Nutrition and Health from Universidade Federal de São Paulo (Unifesp), Campus Baixada Santista, Santos, São Paulo, Brazil.

Patrícia da Graça Leite Speridião, Universidade Federal de São Paulo - Campus Baixada Santista

Ph.D. in Sciences from Universidade Federal de São Paulo, Campus São Paulo, São Paulo, São Paulo, Brazil. Associate Professor at the Department of Health, Education and Society at the Universidade Federal de São Paulo, Campus Baixada Santista, Santos, São Paulo, Brazil

References

Agrawal A. Emergency approaches to neurosurgical conditions [Internet]. Houston, Texas: Springer Editora; 2014. [cited 2015 mar 4]. Available from: http://www.springer.com/us/book/9783319106922#aboutAuthors

American Cancer Society. Cancer facts & figures 2017. [Internet]. Atlanta: American Cancer Society; 2017 [cited 2018 july 24]. Available from: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2017/cancer-facts-and-figures-2017.pdf

Barr R, Collins L, Nayiager T, Doring N, Kennedy C, Halton J, et al. nutritional status at diagnosis in children with cancer. 2: An Assessment by Arm Anthropometry. J Pediatr Hematol Oncol [Internet]. 2011 [cited 2018 feb 24]; 33(3):101-4. Available from: https://pubmed.ncbi.nlm.nih.gov/21368675/. doi: 10.1097/MPH.0b013e3182002a65.

Bauer J, Jürgens H, Frühald MC. Important aspects of nutrition in children with cancer. Adv Nutr [Internet]. 2011 [cited 2018 apr 24]; 2(2): 67-77. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065754/. doi: 10.3945/an.110.000141.

Blackburn GL, Thornton PA. Nutritional assessment of the hospitalized patient. Med. Clin. North Am. 1979;14:1102-8.

Bozzetti F, Arends J, Lundholm K, Micklewright A, Zurcher G, Muscaritoli M. ESPEN Guidelines on Parenteral Nutrition: Non-surgical oncology. Clin Nutr [Internet]. 2009 [cited 2019 feb 24]; 28(4):445-54. Available from: https://pubmed.ncbi.nlm.nih.gov/19477052/. doi: 10.1016/j.clnu.2009.04.011.

Brinksma A, Huizinga G, Sulkers E, Kamps W, Roodbol P, Tissing W. Malnutrition in childhood cancer patients: a review on its prevalence and possible causes. Crit Rev Oncol Hematol [Internet]. 2012 [cited 2018 apr 24];83(2):249-75. Available from: https://europepmc.org/article/med/22264939. doi: 10.1016/j.critrevonc.2011.12.003.

Brinksma A, Huizinga G, Sulkers E, Kamps W, Roodbol P, Tissing W. Malnutrition in childhood cancer patients: a review on its prevalence and possible causes. Crit Rev Oncol Hematol [Internet]. 2012 [cited 2019 feb 4];83(2): 249-75. Available from: https://pubmed.ncbi.nlm.nih.gov/22264939/. DOI: 10.1016/j.critrevonc.2011.12.003.

Collins L, Nayiager T, Doring N, Kennedy C, Webber C, Halton J, et al. Nutritional status at diagnosis in children with cancer I. An assessment by dietary recall--compared with body mass index and body composition measured by dual energy X-ray absorptiometry. J Pediatr Hematol Oncol [Internet]. 2010 [cited 2018 feb 24];32(8):e299-e303. Available from: https://pubmed.ncbi.nlm.nih.gov/20962676/. doi: 10.1097/MPH.0b013e3181e9e43c.

Frisancho AR. Anthropometric Standards for the assessment of growth and nutritional status. Ann Arbor: The University of Michigan Press; 1993.

Frisancho, A. R. Triceps skin fold and upper arm muscle size norms for assessment of nutrition status. Am. J. Clin. Nutr [Internet]. 1974 [cited 2018 aug 2];27(10):1052-8. Available from: https://pubmed.ncbi.nlm.nih.gov/4419774/. doi: 10.1093/ajcn/27.8.1052.

Garófolo A, Caran EM, Silva NS, Lopez FA. Prevalência de desnutrição em crianças com tumores sólidos. Rev Nutr [Internet]. 2005 [citado 2018 feb 24];18(2):193-200. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732005000200003&lng=pt. doi: 10.1590/S1415-52732005000200003.

Garófolo A. Diretrizes para terapia nutricional em crianças com câncer em situação crítica. Rev Nutr [Internet]. 2005 [citado 2018 set 19]; 18(4): 513-27. Disponível em: https://www.researchgate.net/publication/250040872_Diretrizes_para_terapia_nutricional_em_criancas_com_cancer_em_situacao_critica. doi: 10.1590/S1415-52732005000400007.

Grant M, Kravits K. Symptoms and their impact on nutrition. Semin Oncol Nurs [Internet]. 2000 [cited 2018 sep 19]; 16(2):113-21. Available from: https://pubmed.ncbi.nlm.nih.gov/10842780/ doi: 10.1053/on.2000.5738

Huhmann MB, August DA. Review of American society for parenteral and enteral nutrition (A.S.P.E.N.) clinical guidelines for nutrition support in cancer patients: nutrition screening and assessment. Nutr Clin Pract [Internet]. 2008 [cited 2015 feb 24]; 23(2): 182-8. Available from: https://pubmed.ncbi.nlm.nih.gov/18390787/. DOI: 10.1177/0884533608314530

Instituto Nacional de Câncer. Consenso Nacional de Nutrição Oncológica [Internet]. 2a ed. Rio de Janeiro: INCA; 2016 [citado 2020 jun 26]. Disponível em: https://www.inca.gov.br/sites/ufu.sti.inca.local/files//media/document//consenso-nutricao-oncologica-vol-ii-2-ed-2016.pdf

Instituto Nacional de Câncer. Consenso Nacional de Nutrição Oncologica. [Internet]. Rio de Janeiro: INCA; 2009 [citado 2019 fev 11]. Disponível em: http://bvsms.saude.gov.br/bvs/publicacoes/consenso_nacional_nutricao_oncologico.pdf

Instituto Nacional de Câncer. Consenso nacional de nutrição oncológica: paciente pediátrico oncológico [Internet]. Rio de Janeiro: INCA; 2014. [citado 2019 ago 2]. Disponível em: http://www1.inca.gov.br/inca/Arquivos/comunicacao/Consenso_de_Nutricao_Oncologica_Pediatria_PDF_final.pdf

Instituto Nacional de Câncer. Estimativa 2014: incidência de câncer no Brasil [Internet]. Rio de Janeiro: INCA; 2019 [citado 2020 jun 15]. Disponível em: https://www.inca.gov.br/sites/ufu.sti.inca.local/files/media/document/estimativa-2020-incidencia-de-cancer-no-brasil.pdf

Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev [Internet]. 2010 [cited 2018 mar 3];36 (4):277-85. Available from: https://www.researchgate.net/publication/41968708_Kaatsch_PEpidemiology_of_childhood_cancer_Cancer_Treat_Rev_36_277-285. doi: 10.1016/j.ctrv.2010.02.003.

Knab B, Connell PP. Radiotherapy for pediatric brain tumors: when and how. Expert Rev Anticancer Ther [Internet]. 2007 [cited 2019 febr 16];7 (12 Suppl):S69-S77. Available from: https://www.tandfonline.com/.doi/abs/10.1586/14737140.7.12s.S69

Lobato-Mendizábal E, López-Martínez B, Ruiz-Argüelles Gj. A critical review of the prognostic value of the nutritional status at diagnosis in the outcome of therapy of children with acute lymphoblastic leukemia. Rev Investig Clin [Internet]. 2003 [cited 2019 mar 4]; 31-5. Available from: http://www.pubfacts.com/detail/12708161/A-critical-review-of-the-prognostic-value-of-the-nutritional-status-at-diagnosis-in-the-outcome-of-t

Loeffen EAH, Brinksma A, Miedema KGE, Bock GH, Tissing WJE. Clinical implications of malnutrition in childhood cancer patients--infections and mortality. Support Care Cancer 2015;23(1):143-50. doi: 10.1007/s00520-014-2350-9.

Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol [Internet]. 2007 [cited 2018 febr 16];114(2):97-109. Available from: https://pubmed.ncbi.nlm.nih.gov/17618441/ doi: 10.1007/s00401-007-0243-4.

Maia PS, Tsutsumi RC, Pedro BMO, Garófolo A, Petrilli AS, Lopez FA. Nutritional supplementation in pediatric patients with cancer. Rev Soc Bras Aliment Nutr [Internet]. 2010 [cited 2019 feb 24]; 35(1). Available from: https://pdfs.semanticscholar.org/cc83/d73f64cd4491e4546046f1c32a7fb5aad91b.pdf

Onis M, Onyango AW, Borghi E, Siyam A, Chizuru N, Jonathan S. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ [Internet]. 2007 [cited 2018 apr 13];85(9):660-7. Available from: http://www.who.int/growthref/growthref_who_bull.pdf?ua=1. doi: 10.2471/BLT.07.043497

Sala A, Rossi E, Antillon F, Molina, AL, Maselli T, Bonilla M, et al. Nutritional status at diagnosis is related to clinical outcomes in children and adolescents with cancer: a perspective from Central America. Eur J Cancer [Internet]. 2012 [cited 2019 mar 4];48(2):243-52. Available from: https://pubmed.ncbi.nlm.nih.gov/21737253/. doi: 10.1016/j.ejca.2011.06.006

Tazi I, Hidane Z, Zafad S, Harif M, Benchekroun S, Ribeiro R. Nutritional status at diagnosis of children with malignancies in Casablanca. Pediatr Blood Cancer [Internet]. 2008 [cited 2018 feb 24];51(4):495-8. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684256/. doi: 10.1002/pbc.21689.

World Health Organization. Application tools. [Internet]. Geneva: World Health Organization; 2006 [cited 2018 mar 3]. Available from: http://www.who.int/growthref/tools/en/