Toxicidade dos fitoterápicos de interesse do SUS: uma revisão

Ciciane Pereira Marten Fernandes; Samuel Rodrigues Félix; Márcia de Oliveira Nobre

doi:10.5433/1679-0367.2016v37n1p91

Toxicity of herbal medicines with interest to SUS: a review

Authors

Ciciane Pereira Marten Fernandes Universidade Federal de Pelotas
Samuel Rodrigues Félix Universidade Federal de Pelotas
Márcia de Oliveira Nobre Universidade Federal de Pelotas

DOI:

https://doi.org/10.5433/1679-0367.2016v37n1p91

Keywords:

Phytotherapy, Toxic effects, Medicinal plants.

Abstract

Abstract: In Brazil, ever since colonization plants have been used as natural products; thus, the National Health Surveillance Agency has been establishing rules for herbal medicine regulation; in this light, 71 plant species were chosen and empirically used in the country to investigate their medicinal properties. Currently, 12 of these 71 plants have been approved to be used in SUS (Public Health System), the remaining species still need further research. Thusly, this review aimed to seek information from toxicological studies on the plants that have not yet been officially approved, to stimulate new research in the field, promoting an economical and functional impact. In order to obtain the information, the keywords plant name + toxicity and/or toxicological studies were searched in the most prominent databases, both in English and in Portuguese. The ten plants with the most references were included in this review. Among the ten plants assessed, three have all the required studies required by the National Health Surveillance Agency, two of which we recommend the immediate adoption by SUS. In general, three plants have a determined LD50, nine have reproductive toxicity data, and five have not yet shown any sign of toxicity.

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Author Biographies

Ciciane Pereira Marten Fernandes, Universidade Federal de Pelotas

Medical Veterinary Faculty of Veterinary Medicine, Federal Universidade Federal de Pelotas. MA and PhD in Animal Health at the same university.

Samuel Rodrigues Félix, Universidade Federal de Pelotas

Veterinary Medical Faculty of Veterinary Medicine, Universidade Federal de Pelotas. Master's and doctorate from the same university.

Márcia de Oliveira Nobre, Universidade Federal de Pelotas

Medical veterinary Universidade Federal de Pelotas. Master of Veterinary at the same university. PhD in Veterinary Science from the Universidade Federal do Rio Grande do Sul and post-doctorate by the Universidade Federal de Pelotas.

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Published

2016-11-24

How to Cite

Fernandes CPM, Félix SR, Nobre M de O. Toxicity of herbal medicines with interest to SUS: a review. Semin. Cienc. Biol. Saude [Internet]. 2016 Nov. 24 [cited 2025 Feb. 1];37(1):91-104. Available from: https://ojs.uel.br/revistas/uel/index.php/seminabio/article/view/22735

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Issue

Vol. 37 No. 1 (2016)

Section

Artigos

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