Correlation between Rubino's reaction and soluble sheep erythrocyte-receptors in Hansen's patients

Autores/as

  • Claudete Serrano Astolfi Ferreira Universidade Estadual de Londrina
  • Doura Abdul Hamid Universidade Estadual de Londrina
  • Daysi Regina Train Universidade Estadual de Londrina
  • Emerson José Venâncio Universidade Estadual de Londrina
  • Eiko Nakagawa Itano Universidade Estadual de Londrina

DOI:

https://doi.org/10.5433/1679-0367.1994v15n2p117

Palabras clave:

Rubino's reaction, Leprosy, E-receptors, CD2.

Resumen

This study investigated the correlation between either (actors or molecules that interact with formolate sheep's erythrocytes (Rubino's reaction) and T lymphocytes soluble receptors for sheep erythrocytes (Rs2) present at a high level in the serum of Hansen's patients. The analysis of fractions obtained by chromatography on Sephadex G-200 showed positive Rubino's reaction in the fraction that correspond to Rs2 with more than 150 kDa, detected by a specific anti-soluble receptor. Additionally, the level of the soluble receptor present in the serum of Hansen's patients, showing positive or negative Rubino's reaction, was determinated by immunodiffusion (Mancini). The result demonstrated no statistical difference between serum soluble receptor level in positive (7.3 mm) or negative (7.3 mm) Rubino's reactions, giving evidence that the high molecular weight E-soluble receptor is not responsible for Rubino's reactions.


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Biografía del autor/a

Claudete Serrano Astolfi Ferreira, Universidade Estadual de Londrina

Departamento de Patologia Geral – Centro de Ciências Biológicas – Universidade Estadual de Londrina.

Doura Abdul Hamid, Universidade Estadual de Londrina

Departamento de Patologia Geral – Centro de Ciências Biológicas – Universidade Estadual de Londrina

Daysi Regina Train, Universidade Estadual de Londrina

Departamento de Patologia Geral – Centro de Ciências Biológicas – Universidade Estadual de Londrina

Emerson José Venâncio, Universidade Estadual de Londrina

Departamento de Patologia Geral – Centro de Ciências Biológicas – Universidade Estadual de Londrina.

Eiko Nakagawa Itano, Universidade Estadual de Londrina

Departamento de Patologia Geral – Centro de Ciências Biológicas – Universidade Estadual de Londrina.

Publicado

2004-12-15

Cómo citar

1.
Ferreira CSA, Hamid DA, Train DR, Venâncio EJ, Itano EN. Correlation between Rubino’s reaction and soluble sheep erythrocyte-receptors in Hansen’s patients. Semin. Cienc. Biol. Saude [Internet]. 15 de diciembre de 2004 [citado 24 de noviembre de 2024];15(2):117-20. Disponible en: https://ojs.uel.br/revistas/uel/index.php/seminabio/article/view/7006

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