Hepatites B virus serological markers: anti-HBcAg detection in lacking HBsAg individuals as potential risk in the post-transfusion hepatitis b virus
DOI:
https://doi.org/10.5433/1679-0367.1992v13n2p102Keywords:
Hepatitis B Virus, HBsAg, Anti-HBcAg, Post-trans fusion hepatitis.Abstract
Serological markers for hepatitis B virus were analysed in 127 blood samples from prisoners of the 10th Police Substation in the district of Londrina, Parana, for the purpose of selecting blood donors. Antigeno of HBs and HBe as well as antibodies to HBs, HBe and HBc were measured by radioimmunoessay (Abbott Laboratories), in addition to the presence of HBsAg in 5 samples, which would be detected by normal blood bank routine, 8 HBsAg negative samples gave HBc-antibody positive tests in 7and antibodies to both HBc and HBe in one case, totalizing 13 samples which were potentially infectious to a blood transfusion receptor. The importance of searching, not only for HBsAg but also for the antibody to HBe, is stressed for the prevention of post-transfusional hepatitis.
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