Detection of HGV/GBV-C RNA in Healthy Individuals non Carrier of HBV, HIV-1/2 and HCV
DOI:
https://doi.org/10.5433/1679-0367.2004v25n1p39Keywords:
GBV-C/HGV, Blood donors, RT/PCR.Abstract
The GB virus C (GBV-C)/hepatitis G virus (HGV) is a member of the Flaviviridae family. Based on the clinical and epidemiological profiles, this virus can be acquired mainly by parenteral transmission through contaminated blood. It was therefore investigated the presence of GBV-C/HGV RNA in the peripheral blood from healthy blood donors in the abscence of virus markers including HBV surface antigen (HBsAg), HBV core antibody (anti-HBc) and HCV antibody. HIV-1, HIV-2, were also investigated. GBVC RNA was detected by reverse transcriptase and polymerase chain reactions (RT-PCR). It was detected GBV-C RNA in 6/50 (12 %) blood donors. The presence of GBV-C RNA in the abscence of hepatitis B and C infection in young patients and healthy donors could indicate that this virus is capable of independent transmission and does not contribute to liver disease.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2009 Semina: Ciências Biológicas e da Saúde
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
adopts the CC-BY-NC license for its publications, the copyright being held by the author, in cases of republication we recommend that authors indicate first publication in this journal.
This license allows you to copy and redistribute the material in any medium or format, remix, transform and develop the material, as long as it is not for commercial purposes. And due credit must be given to the creator.
The opinions expressed by the authors of the articles are their sole responsibility.
The magazine reserves the right to make normative, orthographic and grammatical changes to the originals in order to maintain the cultured standard of the language and the credibility of the vehicle. However, it will respect the writing style of the authors. Changes, corrections or suggestions of a conceptual nature will be sent to the authors when necessary.
This Journal is licensed with a license Creative Commons Assignment-NonCommercial 4.0 International.
