Trends in antimicrobial resistance among clinical isolates of Staphylococcus aureus in a university hospital of the north of Paraná from 2002 through 2011

Authors

  • Marcia Regina Eches Perugini Universidade Estadual de Londrina
  • Vitor Hugo Perugini Universidade Estadual de Londrina
  • Ana Rúbia Magalhães Ferreira Universidade Estadual de Londrina
  • Caio Ferreira de Oliveira Universidade Estadual de Londrina
  • Guilherme Teixeira Gomes Universidade Estadual de Londrina
  • Bruna Arantes Rodrigues Lima Universidade Estadual de Londrina
  • Ana Paula Dier Pereira Universidade Estadual de Londrina
  • Floristher Elaine Carrara-Marroni Universidade Estadual de Londrina
  • Eliana Carolina Vespero Universidade Estadual de Londrina
  • Marsileni Pelisson Universidade Estadual de Londrina
  • Maria Alice Galvão Ribeiro Universidade Estadual de Londrina

DOI:

https://doi.org/10.5433/1679-0367.2015v36n1Suplp275

Keywords:

Staphylococcus aureus, Resistance, Antimicrobial, Methicillin.

Abstract

Staphylococcus aureus are pathogens with high incidence of nosocomial infections and community and has great ability to acquire resistance. The objective of this study was to determine susceptibility to antimicrobial profiles of S. aureus isolated in Londrina University Hospital, from January 2002 through December 2011. The retrospective analysis of 3,494 S. aureus performed from a database of Clinical Laboratory Microbiology HU sector. Antibiotic resistance was judged according to the criteria recommended by the Clinical Laboratory Standards Institute. The highest percentages of resistance was founding to erythromycin (49.4%), clindamycin and oxacillin (41.8%) and ciprofloxacin (36.5%). In addition, there was a significant reduction in gentamicin resistance rates, and trimethoprim-sulfamethoxazol. All strains studied were susceptible to linezolid. We found that 40% showed reduced susceptibility to vancomycin. These data indicate a possible change in the epidemiology of S. aureus in our region, which can bring impact on the treatment and control of infection by this agent.

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Author Biographies

Marcia Regina Eches Perugini, Universidade Estadual de Londrina

Professor of Department CAP / CCS / UEL - Microbiology the Universidade Estadual de Lodnrina

Vitor Hugo Perugini, Universidade Estadual de Londrina

Medical student at the the Universidade Estadual de Londrina

Ana Rúbia Magalhães Ferreira, Universidade Estadual de Londrina

Resident in medical biology from the State University of Londrina. Master in Microbiology from the the Universidade Estadual de Londrina.

Caio Ferreira de Oliveira, Universidade Estadual de Londrina

Resident in Clinical Analysis at the State University of Londrina.

Guilherme Teixeira Gomes, Universidade Estadual de Londrina

Resident in Clinical Analysis at the Univesidade Estadual de Londrina.

Bruna Arantes Rodrigues Lima, Universidade Estadual de Londrina

Pharmaceutical. Master's Degree in Microbiology at the Universidade Estadual de Londrina.

Ana Paula Dier Pereira, Universidade Estadual de Londrina

Pharmaceutical. Master's Degree in Microbiology at the Universidade Estadual de Londrina.

Floristher Elaine Carrara-Marroni, Universidade Estadual de Londrina

Pharmaceutical. Master's Degree in Microbiology at the Universidade Estadual de Londrina.

Eliana Carolina Vespero, Universidade Estadual de Londrina

Pharmaceutical. Master's Degree in Microbiology at the Universidade Estadual de Londrina.

Marsileni Pelisson, Universidade Estadual de Londrina

Pharmaceutical. Master's Degree in Microbiology at the Universidade Estadual de Londrina.

Maria Alice Galvão Ribeiro, Universidade Estadual de Londrina

Graduação em Biomedicina pela Universidade Federal de Alfenas

Published

2015-03-09

How to Cite

1.
Perugini MRE, Perugini VH, Ferreira ARM, Oliveira CF de, Gomes GT, Lima BAR, et al. Trends in antimicrobial resistance among clinical isolates of Staphylococcus aureus in a university hospital of the north of Paraná from 2002 through 2011. Semin. Cienc. Biol. Saude [Internet]. 2015 Mar. 9 [cited 2024 Nov. 3];36(1Supl):275-82. Available from: https://ojs.uel.br/revistas/uel/index.php/seminabio/article/view/19395