Clinicopathological profile of patients diagnosed with coloretal neoplasia from 27 municipalities of Paraná Southwest (2016-2020).

Autores

  • Bruna Zibetti
  • Eduardo Henrique Porfirio Michalak
  • Francisco Weiss
  • Daniel Rech
  • Janoário Athanazio Souza
  • Carolina Panis

DOI:

https://doi.org/10.5433/2525-555X.2021.v23.n2.45796

Palavras-chave:

Colorectal cancer, epidemiology, clinicopathological data, adenocarcinoma, neoplasm.

Resumo

Colorectal cancer (CRC) represents the neoplasm that affects the segments of the large intestine, with increasing incidence and intense regional variability. In this study, we sought to evaluate the epidemiological and clinical-pathological profile of patients diagnosed with colorectal neoplasia in 27 municipalities attended at the 8th Health Regional of Paraná, according to parameters such as age, size of the primary tumor, lymph node involvement, presence of metastatic disease, tumor staging, among others. To this end, 231 medical records of patients treated at the Francisco Beltrão Cancer Hospital were reviewed, and CRC cases were profiled with subsequent statistical analysis of data. A total of 226 patients were diagnosed with adenocarcinoma. Regarding the tumor's location, it was found that, among individuals with adenocarcinoma, there was a higher frequency in the rectosigmoid region (65.04%). Regarding the staging of patients with adenocarcinoma, most were in stage IIA (T3, N0, M0) (27.43%), and the second-highest percentage was in patients with stage IV (any T or N, M1; 19.03%). A high frequency of adenocarcinoma was observed in patients over 50 years of age, with overweight/obese. Most of these patients did not show evidence of multiple familial polyposes and, in general, they were smokers, alcoholics, and underwent chemotherapy. Despite the regional epidemiologic characteristics concerning pesticides exposure and a high CRC incidence registered in such populations, the disease profile found here is similar to other regions globally, suggesting that other risk factors might be enrolled. 

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Publicado

2023-04-03

Como Citar

Zibetti, B., Michalak, E. H. P., Weiss, F., Rech, D., Souza, J. A., & Panis, C. (2023). Clinicopathological profile of patients diagnosed with coloretal neoplasia from 27 municipalities of Paraná Southwest (2016-2020). Biosaúde, 23(2), 48–56. https://doi.org/10.5433/2525-555X.2021.v23.n2.45796

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